Retinal capillary hemangioma treatment by indocyanine green-mediated photothrombosis

Retinal capillary hemangioma treatment by indocyanine green-mediated photothrombosis

Author Costa, R. A. Google Scholar
Meirelles, R. L. Google Scholar
Cardillo, J. A. Google Scholar
Abrantes, M. L. Google Scholar
Farah, M. E. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract PURPOSE: To describe the clinical, angiographic and optical coherence tomography (OCT) findings of a patient with a large retinal capillary hemangioma who was treated by indocyanine green-mediated photothrombosis.DESIGN: Interventional case report.METHODS: An 18-year,old male patient was treated at a tertiary referral center with a novel laser-dye procedure that uses low-irradiance 810-nm laser and intravenous indocyanine green injection and was prospectively evaluated with fluorescein and indocyanine green angiography, as well as OCT.RESULTS: Vision improved from 20/125 to 20/32 + 1 at 1-year follow-up. Fundus photography showed marked reduction of a 3 disk diameters retinal capillary hemangioma. Both fluorescein and indocyanine green angiography demonstrated reduced tumor perfusion and narrowing of the lesion feeder and draining vessels, as early as 5 days after indocyanine green-mediated photothrombosis; OCT showed immediate decrease in retinal elevation and complete resolution of subretinal fluid within 2 months of treatment. Minimal laser,induced effects were noted in the vicinity of the tumor.CONCLUSIONS: Photothrombosis using low,intensity, 810-nm light to direct laser energy continuously at the tumor after intravenous indocyanine green infusion was effective in restoring macular architecture and improving vision in a patient with a large peripheral retinal capillary hemangioma by means of substantial occlusion of the tumor vasculature and resolution of subretinal fluid. (C) 2003 by Elsevier Science Inc. All rights reserved.
Language English
Date 2003-03-01
Published in American Journal of Ophthalmology. New York: Elsevier B.V., v. 135, n. 3, p. 395-398, 2003.
ISSN 0002-9394 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 395-398
Access rights Closed access
Type Article
Web of Science ID WOS:000181258100026

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