Prevalence and 7-year incidence of Type II diabetes mellitus in a Japanese-Brazilian population: an alarming public health problem

Prevalence and 7-year incidence of Type II diabetes mellitus in a Japanese-Brazilian population: an alarming public health problem

Autor Gimeno, Sueli Godoy Agostinho Autor UNIFESP Google Scholar
Ferreira, Sandra Roberta Gouvea Autor UNIFESP Google Scholar
Franco, Laercio Joel Autor UNIFESP Google Scholar
Hirai, Amelia Toyomi Autor UNIFESP Google Scholar
Matsumura, Luiza Kimiko Autor UNIFESP Google Scholar
Moises, R. S. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo Aims/hypothesis. in 1993, the prevalence of glucose intolerance was studied in a sample of 647 first-generation and second-generation Japanese-Brazilians. Their cohort was followed until 2000, when a second survey was conducted, this included the first and second generations, aged 30 or more years. the aims were to estimate the prevalence of glucose intolerance and 7-yr incidence of Type 11 (non-insulin-dependent) diabetes mellitus in this population.Methods. Prevalence rates were obtained for 1330 subjects examined in 2000. the incidence of diabetes mellitus was calculated for those classified as normal glucose tolerant in 1993 (n=253). A Student's t test and the Cox proportional hazard model were used in data analysis.Results. in the year 2000, higher proportions of subjects were observed in all categories of glucose intolerance than those found in 1993. the overall incidence of diabetes was 30.9 per 1000 per year. A worse profile was observed among incident cases. of diabetes, characterized by higher baseline values of anthropometric and metabolic variables as compared to those who had not developed diabetes. Analysis considering the simultaneous effects of demographic, nutritional and metabolic variables and physical activity levels for the development of diabetes showed that age, sex, waist circumference, fasting and 2-h plasma glucose concentrations were independent predictors.Conclusion/interpretation. Our data point towards a worsening of glucose tolerance status among Japanese-Brazilians, who show one of the highest prevalence rates of diabetes mellitus worldwide. This could reflect their strong genetic susceptibility associated with unfavourable environmental conditions.
Palavra-chave incidence
prevalence
diabetes mellitus
risk factors
Japanese migrants
Idioma Inglês
Data de publicação 2002-12-01
Publicado em Diabetologia. New York: Springer-verlag, v. 45, n. 12, p. 1635-1638, 2002.
ISSN 0012-186X (Sherpa/Romeo, fator de impacto)
Publicador Springer
Extensão 1635-1638
Fonte http://dx.doi.org/10.1007/s00125-002-0963-x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000180041600003
Endereço permanente http://repositorio.unifesp.br/handle/11600/27057

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