Epithelial salivary glands neoplasms in children and adolescents: A forty-four-year experience

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dc.contributor.author Ribeiro, KDB
dc.contributor.author Kowalski, L. P.
dc.contributor.author Saba, LMB
dc.contributor.author Camargo, B. de
dc.date.accessioned 2016-01-24T12:33:37Z
dc.date.available 2016-01-24T12:33:37Z
dc.date.issued 2002-12-01
dc.identifier http://dx.doi.org/10.1002/mpo.10168
dc.identifier.citation Medical and Pediatric Oncology. Hoboken: Wiley-liss, v. 39, n. 6, p. 594-600, 2002.
dc.identifier.issn 0098-1532
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/27056
dc.description.abstract Background. Epithelial neoplasms of salivary gland origin are relatively uncommon in children and adolescents. Over a 44-year period, there were 38 cases affecting children under 19 years of age in our Pediatric Hospital-Based Tumor Registry.Procedure. Medical charts of 38 patients with epithelial neoplasms of salivary glands were reviewed, Data collected included demographic, clinical, and histological characteristics. Statistical analysis included descriptive statistics, Student t-test, and Kaplan-Meier method was used for survival analysis.Results. the mean age was 11.8 years. There was a female preponderance of 1.9:1. the parotid gland was affected in most cases (65.8%). Twenty-seven patients had malignant tumors and eleven patients presented benign neoplasms. Pleomorphic adenoma was the most frequent benign tumor (7 out of 11) and mucoepidermoid carcinoma vas the most frequent malignancy (17 Out of 27), Five-year overall survival rate was 81.6% for patients with malignant tumors. Grade of differentiation was the only significant prognostic factor for patients with mucoepidermoid carcinomas.Conclusions. Epithelial salivary gland tumors are very raw in children. Surgery is the heat option to achieve high cure rates and radiotherapy must have precise indications because of their long-term side effects in young age. (C) 2002 Wiley-Liss, Inc. en
dc.format.extent 594-600
dc.language.iso eng
dc.publisher Wiley-Blackwell
dc.relation.ispartof Medical and Pediatric Oncology
dc.rights Acesso restrito
dc.subject salivary gland neoplasms en
dc.subject childhood cancer en
dc.subject epidemiology en
dc.subject childhood head and neck tumors en
dc.title Epithelial salivary glands neoplasms in children and adolescents: A forty-four-year experience en
dc.type Artigo
dc.rights.license http://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institution Ctr Tratamento & Pesquisa Hosp Canc AC Camorgo
dc.contributor.institution Hosp Canc Registry Coordinator
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Ctr Tratamento & Pesquisa Hosp Canc AC Camorgo, Dept Otorhinolaryngol Head & Neck Surg, BR-01509900 São Paulo, Brazil
dc.description.affiliation Hosp Canc Registry Coordinator, Ctr Tratamento & Pesquisa Hosp Canc AC Camargo, São Paulo, Brazil
dc.description.affiliation Ctr Tratamento & Pesquisa Hosp Canc AC Camorgo, Pathol Res Ctr, BR-01509900 São Paulo, Brazil
dc.description.affiliation Ctr Tratamento & Pesquisa Hosp Canc AC Camorgo, Dept Pediat, BR-01509900 São Paulo, Brazil
dc.identifier.doi 10.1002/mpo.10168
dc.description.source Web of Science
dc.identifier.wos WOS:000178734600010



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