Epithelial salivary glands neoplasms in children and adolescents: A forty-four-year experience

Epithelial salivary glands neoplasms in children and adolescents: A forty-four-year experience

Author Ribeiro, KDB Google Scholar
Kowalski, L. P. Google Scholar
Saba, LMB Google Scholar
Camargo, B. de Google Scholar
Institution Ctr Tratamento & Pesquisa Hosp Canc AC Camorgo
Hosp Canc Registry Coordinator
Universidade Federal de São Paulo (UNIFESP)
Abstract Background. Epithelial neoplasms of salivary gland origin are relatively uncommon in children and adolescents. Over a 44-year period, there were 38 cases affecting children under 19 years of age in our Pediatric Hospital-Based Tumor Registry.Procedure. Medical charts of 38 patients with epithelial neoplasms of salivary glands were reviewed, Data collected included demographic, clinical, and histological characteristics. Statistical analysis included descriptive statistics, Student t-test, and Kaplan-Meier method was used for survival analysis.Results. the mean age was 11.8 years. There was a female preponderance of 1.9:1. the parotid gland was affected in most cases (65.8%). Twenty-seven patients had malignant tumors and eleven patients presented benign neoplasms. Pleomorphic adenoma was the most frequent benign tumor (7 out of 11) and mucoepidermoid carcinoma vas the most frequent malignancy (17 Out of 27), Five-year overall survival rate was 81.6% for patients with malignant tumors. Grade of differentiation was the only significant prognostic factor for patients with mucoepidermoid carcinomas.Conclusions. Epithelial salivary gland tumors are very raw in children. Surgery is the heat option to achieve high cure rates and radiotherapy must have precise indications because of their long-term side effects in young age. (C) 2002 Wiley-Liss, Inc.
Keywords salivary gland neoplasms
childhood cancer
childhood head and neck tumors
Language English
Date 2002-12-01
Published in Medical and Pediatric Oncology. Hoboken: Wiley-liss, v. 39, n. 6, p. 594-600, 2002.
ISSN 0098-1532 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 594-600
Origin http://dx.doi.org/10.1002/mpo.10168
Access rights Closed access
Type Article
Web of Science ID WOS:000178734600010
URI http://repositorio.unifesp.br/handle/11600/27056

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