Antibodies against oxidized low-density lipoprotein in normolipidemic smokers

Antibodies against oxidized low-density lipoprotein in normolipidemic smokers

Autor Zaratin, Águeda Google Scholar
Gidlund, Magnus Google Scholar
Boschcov, Paulo Autor UNIFESP Google Scholar
Castilho, Lucia Google Scholar
Faria, Eliana Cotta de Google Scholar
Instituição Universidade Estadual de Campinas (UNICAMP)
Universidade de São Paulo (USP)
IMTSP
Universidade Federal de São Paulo (UNIFESP)
Resumo Oxidative low-density lipoprotein (LDL) damage caused by oxidants present in cigarette smoke may be involved in the pathogenesis of coronary heart disease,(1) but there is a controversy in published reports on this subject. Gouaze et al(2) demonstrated increased oxidizability in smokers, Siekmeier et al(3) could not confirm these results, and Chen and Loo(4) found an antioxidant property of cigarette smoke extract by measuring its effect on LDL oxidizability in vitro. We evaluated the contribution of cigarette smoking on LDL oxidizability and,plasma levels of antioxidized LDL in a well-defined healthy population of normolipidemic smokers. Blood samples were drawn a few minutes after subjects smoked 1 cigarette to ensure higher blood levels of oxidative products from cigarette smoke.(5).
Idioma Inglês
Data de publicação 2002-09-15
Publicado em American Journal of Cardiology. New York: Excerpta Medica Inc, v. 90, n. 6, p. 651-+, 2002.
ISSN 0002-9149 (Sherpa/Romeo, fator de impacto)
Publicador Excerpta Medica Inc
Extensão 651-+
Fonte http://dx.doi.org/10.1016/S0002-9149(02)02576-6
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000178068600020
Endereço permanente http://repositorio.unifesp.br/handle/11600/26979

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