Practical and comprehensive guidelines for bedside cerebral hemometabolic multitherapeutic optimization

Practical and comprehensive guidelines for bedside cerebral hemometabolic multitherapeutic optimization

Author Cruz, Julio Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract In recent years, noncomprehensive guidelines were proposed for the management of severe acute brain injuries, focusing strictly on two approaches: 1) to maintain cerebral perfusion pressure anywhere above 70 mm Hg; and 2) to maintain arterial carbon dioxide tension levels above 30 torr. Strictly following these propositions, a recently reported prospective controlled study addressed mortality rates of no less than 75-76%, far worse than mortality rates reported before those guidelines were published. As a humanitarian alternative, the present comprehensive guidelines are aimed at addressing practical bedside strategies to manage no only intracranial pressure and cerebral perfusion pressure but also cerebral extraction of oxygen, based on solid previously reported papers which revealed the lowest mortality rates (below 15%) in the pertinent literature, in recent years.
Keywords cerebral extraction of oxygen
intracranial pressure
guidelines
head injury
Language English
Date 2002-09-01
Published in Arquivos de Neuro-psiquiatria. São Paulo, SP: Assoc Arquivos de Neuro- Psiquiatria, v. 60, n. 3A, p. 670-674, 2002.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Assoc Arquivos de Neuro- Psiquiatria
Extent 670-674
Origin http://dx.doi.org/10.1590/S0004-282X2002000400031
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000177767200031
SciELO ID S0004-282X2002000400031 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/26960

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