Hospital-acquired meningitis in patients undergoing craniotomy: incidence, evolution, and risk factors

Hospital-acquired meningitis in patients undergoing craniotomy: incidence, evolution, and risk factors

Autor Reichert, MCF Google Scholar
Medeiros, EAS Google Scholar
Ferraz, FAP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objectives. To establish the incidence of postcraniotomy meningitis, identify etiologic agents. assess patients' medical progress in relation to both length of hospitalization and mortality, and analyze risk factors.Material and Method. This study was developed at Hospital São Paulo, a tertiary university hospital, between August 1995 and January 1998, We conducted a case-control trial, in which 50 pairs of patients were matched.Results. An 8.9%-postcraniotomy meningitis incidence was found. Gram-negative bacilli were the most common etiologic agents isolated. Mortality among the patients was 30%. Mean hospital stay for the patients was 42.9+/-22.1 days; for the controls, mean hospital stay was 19.0+/-11.4 days (P=.00001). Although several risk factors were identified by univariate analysis, including postoperative external ventricular shunt (OR=2.92. CI 95% = 1245-6.865, P=.014),remote site infection (OR = 2.85, CI 95% -0.995-8.173, P=.051), and repeat operation (OR=5.02, CI 95% = 1.569-16.066, P=.007), only repeat operation remained in the multivariate analysis model (OR=3.68. CI 95% = 1.158-11.700, P=.027).Conclusion. Postcraniotomy meningitis resulted in a high mortality rate and a longer hospital stay, with repeat operation identified among the risk factors.
Idioma Inglês
Data 2002-05-01
Publicado em American Journal of Infection Control. St Louis: Mosby, Inc, v. 30, n. 3, p. 158-164, 2002.
ISSN 0196-6553 (Sherpa/Romeo, fator de impacto)
Editor Mosby, Inc
Extensão 158-164
Fonte http://dx.doi.org/10.1067/mic.2002.119925
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000175688800004
URI http://repositorio.unifesp.br/handle/11600/26860

Mostrar registro completo




Arquivos deste item

Arquivos Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item aparece na(s) seguinte(s) coleção(s)