Urinary free cortisol is similar in older and younger women

Urinary free cortisol is similar in older and younger women

Autor Carvalhaes Neto, Nelson Autor UNIFESP Google Scholar
Ramos, Luiz Roberto Autor UNIFESP Google Scholar
Vieira, Jose Gilberto Henriques Autor UNIFESP Google Scholar
Kater, Claudio Elias Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The increased cortisol secretion that occurs with aging is associated with characteristics of frailty. in this study we investigated whether healthy elderly women excrete increased amounts of urinary free cortisol (UFC) when compared to younger women. Twenty-four-hour UFC levels were measured in 25 elderly (70 to 87 years of age; median: 74) and 24 younger (19 to 59 years of age; median: 46) community-living women. All subjects were healthy and cognition was unimpaired. No differences in 24-hr UFC were observed between elderly and younger women (54.2 +/- 28.0 and 45.1 +/- 15.6 mug/24 hr, respectively) and no correlation was found between 24-hr UFC and age. Also, elderly and younger women had similar 24-hr urinary volumes (1366 +/- 531 and 1514 +/- 412 ml 24hr, respectively) that did not correlate with UFC. in conclusion, older and younger healthy women have similar 24-hr UFC levels, possibly reflecting a comparable adrenocortical secretion of cortisol.
Idioma Inglês
Data 2002-04-01
Publicado em Experimental Aging Research. Philadelphia: Taylor & Francis Inc, v. 28, n. 2, p. 163-168, 2002.
ISSN 0361-073X (Sherpa/Romeo, fator de impacto)
Editor Taylor & Francis Inc
Extensão 163-168
Fonte http://dx.doi.org/10.1080/03610730252800175
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000174104800003
URI http://repositorio.unifesp.br/handle/11600/26828

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