COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases

COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases

Autor Piovesan, E. J. Google Scholar
Zukerman, Eliova Autor UNIFESP Google Scholar
Kowacs, P. A. Google Scholar
Werneck, L. C. Google Scholar
Instituição Univ Fed Parana
Universidade Federal de São Paulo (UNIFESP)
Resumo The idiopathic stabbing headache (ISH) is characterized by a stabbing pain of short duration, variable localization and an errant evolution pattern. As its biological mechanisms are unknown and the treatment options are little effective, this disorder shows a strong impact on the patient's life. Two females and one male, aged 76, 66 and 72 years, respectively, started presenting ISH within 20 days after the onset of a stroke. All the patients were treated for the ISH with celecoxib, a COX-2 specific inhibitor, with full recovery from ISH up to 6 days after it was first administered. the interruption of the drug 60 days after the treatment with celecoxib induced again the appearance of algic symptoms in two patients. We concluded that cerebrovascular diseases (CD) can lead to ISH and that the COX-2 inhibitor can be an effective prophylactic drug for ISH after CD.
Palavra-chave celecoxib
idiopathic stabbing headache
stroke
treatment
Idioma Inglês
Data de publicação 2002-04-01
Publicado em Cephalalgia. Oxford: Blackwell Publishing Ltd, v. 22, n. 3, p. 197-200, 2002.
ISSN 0333-1024 (Sherpa/Romeo, fator de impacto)
Publicador Blackwell Publishing Ltd
Extensão 197-200
Fonte http://dx.doi.org/10.1046/j.1468-2982.2002.00346.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000176027100007
Endereço permanente http://repositorio.unifesp.br/handle/11600/26824

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta