Identification of bradykinins in solitary wasp venoms

Identification of bradykinins in solitary wasp venoms

Autor Konno, K. Google Scholar
Palma, M. S. Google Scholar
Hitara, I. Y. Google Scholar
Juliano, M. A. Google Scholar
Juliano, L. Google Scholar
Yasuhara, T. Google Scholar
Instituição São Paulo State Univ
FAPESP
Universidade Federal de São Paulo (UNIFESP)
Tokyo Univ Agr
Resumo Bradykinins were identified in three solitary wasp venoms. Purification and characterization of the venom extract of the scoliid wasp Megacampsomeris prismatica led to the identification of bradykinin and threonine(6)-bradykinin as the major peptide components. the survey of a number of extracts from solitary wasp venom by MALDI-TOF MS revealed that the venoms of two other scoliid wasps, Campsomeriella annulata annulata and Carinoscolia melanosoma fascinata, also contained Thr(6)-BK as one of the major components. Thus, this study showed the presence of bradykinins in some of the solitary wasp venoms. Moreover, it indicated that these peptides play a major role in their paralyzing action for prey capture because these bradykinins have been shown to block the synaptic transmission of the nicotinic acetylcholine receptor in the insect central nervous system. (C) 2001 Elsevier B.V. All rights reserved.
Palavra-chave bradykinin
solitary wasp
venom
MALDI-TOF MS
Idioma Inglês
Data de publicação 2002-03-01
Publicado em Toxicon. Oxford: Pergamon-Elsevier B.V., v. 40, n. 3, p. 309-312, 2002.
ISSN 0041-0101 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 309-312
Fonte http://dx.doi.org/10.1016/S0041-0101(01)00230-6
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000173055800009
Endereço permanente http://repositorio.unifesp.br/handle/11600/26769

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