Correlation between plasma and salivary cortisol levels in preterm infants

Correlation between plasma and salivary cortisol levels in preterm infants

Autor Calixto, C. Google Scholar
Martinez, F. E. Google Scholar
Jorge, S. M. Google Scholar
Moreira, A. C. Google Scholar
Martinelli, C. E. Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Resumo We sought to determine correlations between plasma and salivary cortisol levels in preterm infants in the basal state and after adrenocorticotropic hormone (ACTH) stimulation during the First week of life. Infants (n = 48) were given ACTH or saline solution; each injection was separated by 24 hours. Salivary and plasma cortisol levels correlated at baseline (r = 0.67, P < .0001) and I hour after ACTH stimulation (r = 0.40, P = .0047). ACTH increased cortisol levels in plasma from 12.3 +/- 6.4 to 30.3 +/- 13.2 mug/dL (P < .0001) and in saliva from 1.0 +/- 0.8 to 2.6 +/- 1.0 mug/dL (P < .0001). the adrenal response to ACTH can be detected in the saliva of premature newborns during the first week of life.
Idioma Inglês
Data de publicação 2002-01-01
Publicado em Journal of Pediatrics. New York: Mosby-Elsevier, v. 140, n. 1, p. 116-118, 2002.
ISSN 0022-3476 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 116-118
Fonte http://dx.doi.org/10.1067/mpd.2002.120765
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000173670000022
Endereço permanente http://repositorio.unifesp.br/handle/11600/26715

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