An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa

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dc.contributor.author Abe, Cecilia Mari [UNIFESP]
dc.contributor.author Knutton, Stuart
dc.contributor.author Pedroso, Margareth Z. [UNIFESP]
dc.contributor.author Freymuller, Edna [UNIFESP]
dc.contributor.author Gomes, Tania Aparecida Tardelli [UNIFESP]
dc.date.accessioned 2016-01-24T12:31:29Z
dc.date.available 2016-01-24T12:31:29Z
dc.date.issued 2001-09-25
dc.identifier http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x
dc.identifier.citation Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001.
dc.identifier.issn 0378-1097
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/26628
dc.description.abstract The pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved. en
dc.format.extent 199-205
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Fems Microbiology Letters
dc.rights Acesso aberto
dc.subject enteroaggregative en
dc.subject Escherichia coli en
dc.subject invasion en
dc.subject virulence properties en
dc.subject adherence en
dc.title An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Univ Birmingham
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.description.affiliation Univ Birmingham, Inst Child Hlth, Birmingham B4 6NH, W Midlands, England
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, Brazil
dc.identifier.doi 10.1111/j.1574-6968.2001.tb10841.x
dc.description.source Web of Science
dc.identifier.wos WOS:000171422500011



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