Pre-parturition profile of steroids and prostaglandin in cows with or without foetal membrane retention

Pre-parturition profile of steroids and prostaglandin in cows with or without foetal membrane retention

Autor Wischral, A. Google Scholar
Verreschi, ITN Google Scholar
Lima, S. B. Google Scholar
Hayashi, L. F. Google Scholar
Barnabe, R. C. Google Scholar
Instituição Univ Fed Rural Pernambuco
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo Retained foetal membranes in cattle is one of the most common complications associated to the reduction in milk yield and impaired fertility in dairy cattle. in order to determine some endocrine mechanisms controlling parturition and delivery of foetal membranes, plasma concentrations of steroids and prostanoids were determined in 20 healthy Holstein cows. Samples were taken within the interval of 5 days pre-parturition to 12 h after calving. Progesterone (P-4) levels were similar in cows with (PR) and without (NPR) placental retention. While the estradiol-17 beta (E-2) peak at parturition was lower in PR than in NPR cows, cortisol levels were greater in PR cows 12 and 24 h pre-parturition. the Prostaglandin F-2 alpha metabolite (PGFM) levels were higher at parturition in NPR compared with the PR group, but 12h later, these levels in the PR group increased so that concentrations were greater as compared with NPR cows. the Prostaglandin E-2 metabolite (PGEM), 24, 48 and 72 h pre-parturition, were higher in PR cows. However, the PGFM:PGEM ratio was greater in cows up NPR at all time when included, indicating the importance of higher levels of Prostaglandin F-2 alpha (PGF(2 alpha)) than Prostaglandin E-2 (PGE(2)) for normal placental delivery. in conclusion, placental retention was related to both estrogen and PGF(2 alpha) deficiency, which may be a consequence of metabolic stress leading to PGE2 and maternal cortisol synthesis before parturition. (C) 2001 Elsevier Science B.V All rights reserved.
Palavra-chave placenta
bovine
prostaglandin F-2 alpha
prostaglandin E-2
steroids
Idioma Inglês
Data de publicação 2001-09-15
Publicado em Animal Reproduction Science. Amsterdam: Elsevier B.V., v. 67, n. 3-4, p. 181-188, 2001.
ISSN 0378-4320 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 181-188
Fonte http://dx.doi.org/10.1016/S0378-4320(01)00119-1
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000171061900005
Endereço permanente http://repositorio.unifesp.br/handle/11600/26627

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