Traumatic brain ischemia during neuro intensive care

Traumatic brain ischemia during neuro intensive care

Autor Cruz, Julio Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo In non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic parameters have been misinterpreted, or when cerebral blood flow (CBF) alone has been addressed in a biased fashion, without mandatory metabolic data. Indeed, comprehensive and unbiased studies focusing on global cerebral metabolic activity have invariably revealed a condition of normal coupling between reduced CBF and oxygen consumption in the early postinjury hours, which is then followed by a prolonged, sustained pattern of relative cerebral hyperperfusion (the opposite of ischemia). Accordingly, traumatic brain ischemia during intensive care represents myth rather than fact.
Palavra-chave head injury
cerebral metabolism
cerebral blood flow
brain ischemia
Idioma Inglês
Data de publicação 2001-09-01
Publicado em Arquivos de Neuro-psiquiatria. São Paulo, SP: Assoc Arquivos de Neuro- Psiquiatria, v. 59, n. 3A, p. 479-482, 2001.
ISSN 0004-282X (Sherpa/Romeo, fator de impacto)
Publicador Assoc Arquivos de Neuro- Psiquiatria
Extensão 479-482
Fonte http://dx.doi.org/10.1590/S0004-282X2001000400001
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000170727800001
SciELO S0004-282X2001000400001 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/26618

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