Autor |
Bortolai, A.
![]() Melaragno, M. I. ![]() |
Instituição | Universidade Federal de São Paulo (UNIFESP) |
Resumo | Lymphocyte cultures from five patients with chromosomal mosaicism (two 47,XY,+21/46,XY, one 47,XX,+21/46,XX, one 45,X/46,XX, and one 47,XXY/46,XY) were studied using sister chromatid differential staining technique for cell kinetic evaluation: Aneuploid and normal cell lines were compared to identify changes in cellular proliferation ire vitro that could be related to cellular selective advantage and cell-line-proportion changes occurring with age. Comparison of the percentage of cells in different cell generations in 48, 72, and 96 h-cultures shows no differences between the aneuploid and normal cell lines indicating that cell-cycle kinetics is similar in these cells in vitro. (C) 2001 Editions scientifiques et medicales Elsevier SAS. |
Palavra-chave |
chromosomal mosaicism
cell-cycle cell selection Down syndrome Turner syndrome Klinefelter syndrome |
Idioma | Inglês |
Data de publicação | 2001-04-01 |
Publicado em | Annales de Genetique. Paris Cedex 15: Editions Scientifiques Medicales Elsevier, v. 44, n. 2, p. 93-97, 2001. |
ISSN | 0003-3995 (Sherpa/Romeo, fator de impacto) |
Publicador | Elsevier B.V. |
Extensão | 93-97 |
Fonte |
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Direito de acesso | Acesso restrito |
Tipo | Artigo |
Web of Science | WOS:000170848900009 |
Endereço permanente | http://repositorio.unifesp.br/handle/11600/26517 |
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