Cytotoxic T cells and mycobacteria

Cytotoxic T cells and mycobacteria

Author Silva, Celio L. Google Scholar
Bonato, Vania LD Google Scholar
Lima, Karla M. Google Scholar
Coelho-Castelo, Arlete AM Google Scholar
Faccioli, Lucia H. Google Scholar
Sartori, Alexandrina Google Scholar
De Souza, Ana O. Google Scholar
Leao, Sylvia Cardoso Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract How the immune system kills Mycobacterium tuberculosis is still a puzzle. the classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
Keywords cytotoxic T lymphocyte
macrophage activation
cellular immune response
DNA vaccine
gene therapy
Mycobacterium tuberculosis
Language English
Date 2001-04-01
Published in Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 197, n. 1, p. 11-18, 2001.
ISSN 0378-1097 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 11-18
Access rights Open access Open Access
Type Review
Web of Science ID WOS:000167980100002

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