A follow-up study of Toxoplasma gondii infection in southern Brazil

A follow-up study of Toxoplasma gondii infection in southern Brazil

Autor Silveira, C. Google Scholar
Belfort, R. Google Scholar
Muccioli, C. Google Scholar
Abreu, M. T. Google Scholar
Martins, M. C. Google Scholar
Victoria, C. Google Scholar
Nussenblatt, R. B. Google Scholar
Holland, G. N. Google Scholar
Instituição Clin Silveira
Universidade Federal de São Paulo (UNIFESP)
Fed Univ Pelotas
Univ Calif Los Angeles
Resumo PURPOSE: To understand better the natural history of ocular toxoplasmosis by reexamining a well characterized population in Southern Brazil,METHODS: Ophthalmological examination and serologic tests for Toxoplasma gondii infection were performed in 1997 on 383 individuals who had undergone the same evaluation in 1990.RESULTS: of 109 seronegative subjects in 1990, 21 (19.3%) became seropositive by 1997, and 2 (1.5% of previously seronegative patients; 9.5% of those known to have seroconverted) developed ocular toxoplasmosis. Seroconversion occurred more frequently in individuals under 17 years of age (16 of 46 patients, 34.8%) than in those greater than 17 years of age (5 of 63 patients, 7.9%; p = 0.002), of 131 seropositive individuals who did not have ocular lesions in 1990, 11 (8.3%) had typical toxoplasmic lesions in 1997, of the 13 individuals with non-specific hyperpigmented small retinal lesions in 1990, 3 (23%) presented with typical lesions in 1997.CONCLUSIONS: Acquired T. gondii infection can result in late development of ocular lesions. Small, non-specific hyperpigmented retinal lesions may represent sites of T. gondii infection in seropositive individuals, (Am J Ophthalmol 2001;131:351-354, (C) 2001 by Elsevier Science Inc. All rights reserved.).
Idioma Inglês
Data de publicação 2001-03-01
Publicado em American Journal of Ophthalmology. New York: Elsevier B.V., v. 131, n. 3, p. 351-354, 2001.
ISSN 0002-9394 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 351-354
Fonte http://dx.doi.org/10.1016/S0002-9394(00)00830-8
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000167339400010
Endereço permanente http://repositorio.unifesp.br/handle/11600/26499

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