Oral colonization by Candida spp. among AIDS household contacts

Oral colonization by Candida spp. among AIDS household contacts

Autor Milan, E. P. Google Scholar
Kallas, E. G. Google Scholar
Costa, PRD Google Scholar
Matta, Daniel Archimedes da Autor UNIFESP Google Scholar
Colombo, A. L. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Hosp Servidor Publ Estadual Francisco Morato Oliv
Univ Fed Rio Grande Norte
Resumo This study was designed to investigate the oral yeast colonization rate of household contacts of AIDS patients. Sixty-four AIDS household contacts were sequentially enrolled along with 103 HIV-negative blood bank donors (control group). Samples were obtained by swabbing the oral mucosa. Yeast isolates were identified by classical methods and antifungal susceptibility testing was performed according to NCCLS microbroth assay. Candida spp. was recovered from the oral cavity of 33% of the AIDS household contacts, in contrast with 14% of the control group (P = 0.003 or P = 0.04 after adjusting for oral prosthesis use). Candida albicans was the most frequently isolated species in both groups. All of the isolates were susceptible to fluconazole, itraconazole and ketoconazole. in conclusion, we were able to demonstrate a higher colonization rate in the AIDS household contacts group compared with the control group. No resistant isolates to antifungal drugs was observed. We suggest that the contact with AIDS patients may play a role as a risk factor for developing oral colonization by Candida spp.
Palavra-chave Candida
candidosis
colonization
AIDS
epidemiology
Idioma Inglês
Data de publicação 2001-01-01
Publicado em Mycoses. Berlin: Blackwell Wissenschafts-verlag Gmbh, v. 44, n. 7-8, p. 273-277, 2001.
ISSN 0933-7407 (Sherpa/Romeo, fator de impacto)
Publicador Blackwell Wissenschafts-verlag Gmbh
Extensão 273-277
Fonte http://dx.doi.org/10.1111/j.1439-0507.2001.00652.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000171987000004
Endereço permanente http://repositorio.unifesp.br/handle/11600/26459

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