Evaluation of the short-form 36-item questionnaire to measure health-related quality of life in patients with idiopathic pulmonary fibrosis

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dc.contributor.author Martinez, Tieko Y. [UNIFESP]
dc.contributor.author Pereira, Carlos A. C. [UNIFESP]
dc.contributor.author Santos, Manuel L. dos [UNIFESP]
dc.contributor.author Ciconelli, Rozana M. [UNIFESP]
dc.contributor.author Guimarães, Sandra M. [UNIFESP]
dc.contributor.author Martinez, JAB
dc.date.accessioned 2016-01-24T12:31:06Z
dc.date.available 2016-01-24T12:31:06Z
dc.date.issued 2000-06-01
dc.identifier http://dx.doi.org/10.1378/chest.117.6.1627
dc.identifier.citation Chest. Northbrook: Amer Coll Chest Physicians, v. 117, n. 6, p. 1627-1632, 2000.
dc.identifier.issn 0012-3692
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/26316
dc.description.abstract Objective: To validate the use of the 36-item short-form questionnaire (SF-36) for measuring health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).Design: Observational data at a single point in time,Setting: A specialized outpatient respiratory clinic.Participants: Thirty-four patients (mean +/- SE age, 58.29 +/- 1.87 years) with IPF and no significant comorbidity. A matched control group for HRQL measurements was composed of 34 normal subjects (mean age, 58.00 +/- 1.89 years).Measurements and results: Dyspnea was measured by the baseline dyspnea index (BDI). Respiratory function evaluation included FVC, FEV1, and resting; arterial blood gases. IPF patients showed a mean BDI score of 5.21 +/- 0.46. the mean FVC and FEV1 values were 62.41 +/- 2.96% and 66.41 +/- 3.33%, respectively. the mean Pao(2) was 67 +/- 2.51 mm Hg, and the mean Paco(2) was 37 +/- 1.05 mm Hg. Patients scored significantly worse than control subjects with respect to the SF-36 domains of physical functioning, physical role, general health perceptions, vitality, social functioning, emotional role, and mental health index. BDI scores were significantly correlated with five SF-36 components, and FVC and FEV1 were significantly correlated with two SF-36 components. Significant negative correllations were found between arterial pH and four SF-36 domains.Conclusions: Patients with IPF have a significant impairment of HRQL in both physical and psychological functioning. Dyspnea is the most important factor influencing the quality of life in these subjects. the SF-36 questionnaire is a valid instrument to evaluate HRQL in IPF patients. en
dc.format.extent 1627-1632
dc.language.iso eng
dc.publisher Amer Coll Chest Physicians
dc.relation.ispartof Chest
dc.rights Acesso aberto
dc.subject dyspnea en
dc.subject idiopathic pulmonary fibrosis en
dc.subject lung function en
dc.subject quality of life en
dc.title Evaluation of the short-form 36-item questionnaire to measure health-related quality of life in patients with idiopathic pulmonary fibrosis en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Div Pulm, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Div Rheumatol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Div Pulm, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Div Rheumatol, São Paulo, Brazil
dc.identifier.doi 10.1378/chest.117.6.1627
dc.description.source Web of Science
dc.identifier.wos WOS:000087666300021



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