Evaluation of the short-form 36-item questionnaire to measure health-related quality of life in patients with idiopathic pulmonary fibrosis

Evaluation of the short-form 36-item questionnaire to measure health-related quality of life in patients with idiopathic pulmonary fibrosis

Autor Martinez, Tieko Y. Autor UNIFESP Google Scholar
Pereira, Carlos A. C. Autor UNIFESP Google Scholar
Santos, Manuel L. dos Autor UNIFESP Google Scholar
Ciconelli, Rozana M. Autor UNIFESP Google Scholar
Guimarães, Sandra M. Autor UNIFESP Google Scholar
Martinez, JAB Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: To validate the use of the 36-item short-form questionnaire (SF-36) for measuring health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).Design: Observational data at a single point in time,Setting: A specialized outpatient respiratory clinic.Participants: Thirty-four patients (mean +/- SE age, 58.29 +/- 1.87 years) with IPF and no significant comorbidity. A matched control group for HRQL measurements was composed of 34 normal subjects (mean age, 58.00 +/- 1.89 years).Measurements and results: Dyspnea was measured by the baseline dyspnea index (BDI). Respiratory function evaluation included FVC, FEV1, and resting; arterial blood gases. IPF patients showed a mean BDI score of 5.21 +/- 0.46. the mean FVC and FEV1 values were 62.41 +/- 2.96% and 66.41 +/- 3.33%, respectively. the mean Pao(2) was 67 +/- 2.51 mm Hg, and the mean Paco(2) was 37 +/- 1.05 mm Hg. Patients scored significantly worse than control subjects with respect to the SF-36 domains of physical functioning, physical role, general health perceptions, vitality, social functioning, emotional role, and mental health index. BDI scores were significantly correlated with five SF-36 components, and FVC and FEV1 were significantly correlated with two SF-36 components. Significant negative correllations were found between arterial pH and four SF-36 domains.Conclusions: Patients with IPF have a significant impairment of HRQL in both physical and psychological functioning. Dyspnea is the most important factor influencing the quality of life in these subjects. the SF-36 questionnaire is a valid instrument to evaluate HRQL in IPF patients.
Palavra-chave dyspnea
idiopathic pulmonary fibrosis
lung function
quality of life
Idioma Inglês
Data de publicação 2000-06-01
Publicado em Chest. Northbrook: Amer Coll Chest Physicians, v. 117, n. 6, p. 1627-1632, 2000.
ISSN 0012-3692 (Sherpa/Romeo, fator de impacto)
Publicador Amer Coll Chest Physicians
Extensão 1627-1632
Fonte http://dx.doi.org/10.1378/chest.117.6.1627
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000087666300021
Endereço permanente http://repositorio.unifesp.br/handle/11600/26316

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