Combination of antidepressants and psychological treatments for bulimia nervosa: a systematic review

Combination of antidepressants and psychological treatments for bulimia nervosa: a systematic review

Autor Bacaltchuk, J. Google Scholar
Trefiglio, R. P. Google Scholar
Oliveira, I. R. Google Scholar
Hay, P. Google Scholar
Lima, M. S. Google Scholar
Mari, J. J. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade Federal da Bahia (UFBA)
Univ Adelaide
Fed Univ Pelotas
Resumo Background: This review assessed the effect of a combination of antidepressants plus psychological approaches compared to each single treatment for bulimia nervosa.Method: Trials were included in two meta-analyses: single antidepressants versus combination and single psychological approaches versus combination. Methodological quality and homogeneity of results were assessed. Dichotomous outcomes were analysed by calculating relative risks (RR).Results: Five trials were included in meta-analysis I and 7 in meta-analysis 2. Remission rates were 42% for combination versus 23% for antidepressants (RR = 1.38; 95% CI = 0.98-1.93; P = 0.06) and 36% for psychological approaches compared to 49% for combination (RR = 1.21; P = 0.03). Drop-out rates were 16% for psychological approaches and 30% for combination (RR = 0.57; 95% CI = 0.38-0.088; P = 0.11).Conclusion: Efficacy of combined treatments was superior to single approaches. When antidepressants were combined to treatment, acceptability of psychological approaches was significantly reduced.
Palavra-chave antidepressants
bulimia nervosa
meta-analysis
psychotherapy
systematic review
Idioma Inglês
Data de publicação 2000-04-01
Publicado em Acta Psychiatrica Scandinavica. Copenhagen: Munksgaard Int Publ Ltd, v. 101, n. 4, p. 256-264, 2000.
ISSN 0001-690X (Sherpa/Romeo, fator de impacto)
Publicador Munksgaard Int Publ Ltd
Extensão 256-264
Fonte http://dx.doi.org/10.1111/j.1600-0447.2000.tb10923.x
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:000086277500002
Endereço permanente http://repositorio.unifesp.br/handle/11600/26289

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