Gastrinaemia and G-cell density in the antral gastrocystoplasty: an experimental study in rats

Gastrinaemia and G-cell density in the antral gastrocystoplasty: an experimental study in rats

Autor Ortiz, Valdemar Autor UNIFESP Google Scholar
Goldenberg, Saul Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective To evaluate gastrinaemia and G-cell density in the antrum incorporated into the bladder of rats after antrocystoplasty.Materials and methods Thirty-two adult, female Wistar EPM-1 rats (body weight 200-220 g) were divided into four equal groups that underwent; group 1, no treatment (controls); group 2, a sham operation: group 3, antrectomy; and group 4, antrocystoplasty. the rats were assessed 2 months after treatment, and gastrinaemia and the G-cell density determined in the antrum mucosa incorporated into the bladder,Results Compared with group 1, serum gastrin was significantly lower in group 3 (P<0.05) and the G-cell density lower in group 4 (P<0.05), although there was no decrease in gastrinaemia in group 4,Conclusion Antrocystoplasty in rats did not affect gastrinaemia but reduced the number of G cells in the antrum incorporated into the bladder.
Palavra-chave gastrocystoplasty
gastrin
gastric antrum
G cells
bladder augmentation
Idioma Inglês
Data de publicação 2000-03-01
Publicado em Bju International. Oxford: Blackwell Science Ltd, v. 85, n. 4, p. 532-534, 2000.
ISSN 1464-4096 (Sherpa/Romeo, fator de impacto)
Publicador Blackwell Science Ltd
Extensão 532-534
Fonte http://dx.doi.org/10.1046/j.1464-410x.2000.00472.x
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000085858200031
Endereço permanente http://repositorio.unifesp.br/handle/11600/26253

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