Predictive score for the systemic treatment of unruptured ectopic pregnancy with a single dose of methotrexate

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dc.contributor.author Elito Junior, Julio [UNIFESP]
dc.contributor.author Reichmann, A. P.
dc.contributor.author Nakamura, Mary Uchiyama [UNIFESP]
dc.contributor.author Camano, Luiz
dc.date.accessioned 2016-01-24T12:30:54Z
dc.date.available 2016-01-24T12:30:54Z
dc.date.issued 1999-11-01
dc.identifier http://dx.doi.org/10.1016/S0020-7292(99)00114-9
dc.identifier.citation International Journal of Gynecology & Obstetrics. Clare: Elsevier Sci Ireland Ltd, v. 67, n. 2, p. 75-79, 1999.
dc.identifier.issn 0020-7292
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/26167
dc.description.abstract Objective: To evaluate the efficacy of a predictive score for the systemic treatment of unruptured ectopic pregnancy with a single dose of methotrexate in order to select the best cases for the medical treatment. Method: Our study included 40 patients. the inclusion criteria were: hemodynamic stability; adnexal mass less than or equal to 3.5 cm; desire of future pregnancy; and a written permission to participate in the study. All patients were treated with a single dose of methotrexate (50 mg/m(2) i.m.). A predictive score was elaborated based on four parameters: initial levels of beta-hCG, aspects of the image at ultrasound (hematosalpinx, tubal ring or live embryo), size of the mass, vascular flow of the color Doppler. Each parameter received a grade from 0 to 2. Grade 0 represented an unfavorable situation, grade 1 a borderline situation and grade 2 a favorable situation. Results: the success rate with a single dose of methotrexate was 75% (30/40). in the present study the cut off grade was 5, because the majority of patients with grade 2 5 were treated successfully (29/30 - 97%), while those with grade < 5 failed. Conclusion: the predictive score helps us to indicate the best cases for the medical treatment. Therefore, we do not advise it when the grade is < 5. However, we can predict a good evolution of the treatment when the grade is greater than or equal to 5. (C) 1999 International Federation of Gynecology and Obstetrics. en
dc.format.extent 75-79
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof International Journal of Gynecology & Obstetrics
dc.rights Acesso restrito
dc.subject ectopic pregnancy en
dc.subject predictive score en
dc.subject methotrexate en
dc.subject single dose en
dc.subject medical treatment en
dc.title Predictive score for the systemic treatment of unruptured ectopic pregnancy with a single dose of methotrexate en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Radiol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Obstet, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Radiol, São Paulo, Brazil
dc.identifier.doi 10.1016/S0020-7292(99)00114-9
dc.description.source Web of Science
dc.identifier.wos WOS:000083712900002



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