Hysteroscopic evaluation of the endometrium of post-menopausal patients with breast cancer before and after tamoxifen use

Hysteroscopic evaluation of the endometrium of post-menopausal patients with breast cancer before and after tamoxifen use

Autor Goncalves, MAG Google Scholar
Goncalves, Wagner Jose Autor UNIFESP Google Scholar
Matias, M. M. Google Scholar
Nazario, ACP Google Scholar
Lima, G. R. de Google Scholar
Baracat, E. C. Google Scholar
Instituição Pontificia Univ Catolica Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
Porto Alegre Gen Hosp
Resumo Objective: To evaluate by hysteroscopy and histopathology the influence of tamoxifen in the endometrium df post-menopausal women with previous breast cancer. Method: Out of 46 patients studied, 20 of them had been using tamoxifen for an average length of 12 months, and are still being followed-up. Hysteroscopy with endometrial biopsy was performed before and after the use of the drug. Results: the prevalence of endometrial activity before and after this hormoniotherapy was the same, i.e. 10.0%, showing a non-significant variation. Conclusion: the hormoniotherapy with tamoxifen has not increased the endometrial proliferactive activity of postmenopausal patients with breast cancer. the most common hysteroscopical finding was numerous vesicles disseminated throughout the uterine cavity probably due to atrophy of the endometrium, (C) 1999 International Federation of Gynecology and Obstetrics.
Palavra-chave breast cancer
hysteroscopy
tamoxifen
endometrial disease
menopause
Idioma Inglês
Data de publicação 1999-09-01
Publicado em International Journal of Gynecology & Obstetrics. Clare: Elsevier Sci Ireland Ltd, v. 66, n. 3, p. 273-279, 1999.
ISSN 0020-7292 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 273-279
Fonte http://dx.doi.org/10.1016/S0020-7292(99)00079-X
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000082839500006
Endereço permanente http://repositorio.unifesp.br/handle/11600/26135

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