Patients with epileptic seizures and cerebral lesions who underwent lesionectomy restricted to or associated with the adjacent irritative area

Patients with epileptic seizures and cerebral lesions who underwent lesionectomy restricted to or associated with the adjacent irritative area

Autor Rassi Neto, Aziz Autor UNIFESP Google Scholar
Ferraz, Fernando Patriani Autor UNIFESP Google Scholar
Campos, Carlos R. Google Scholar
Braga, Fernando Menezes Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Purpose: To analyze the best surgical procedure for patients with epileptic seizures and cerebral lesions-i.e., resection restricted to the lesion or resection associated with the adjacent irritative area-based on the clinical evolution of patients' seizure outcome and electroencephalographic (EEG) and electrocorticographic (ECoG) findings.Methods: This study comprised 37 patients with epileptic seizures and cerebral lesions, ranging in age from 9 to 66 years. Patients were divided into two groups: Group 1 consisted of 21 patients with medically intractable epilepsy, Group 2 of 16 patients with medically controlled epilepsy. Eleven of the 21 patients in Group 1 (Subgroup A) underwent surgical resection of the cerebral lesion and adjacent irritative area as shown by ECoG. for the remaining 10 patients in Group 1 (Subgroup B), the resection was restricted to the lesion. the 16 patients in Group 2 all underwent lesionectomies.Results: of the 11 patients in group 1 who underwent resection of the cerebral lesion and adjacent irritative area, 91% became seizure free. Sixty percent of the remaining patients in group 1 whose resections were restricted to the lesion also became seizure free, as did all the patients in group 2. An overall analysis of the EEGs for all patients showed a statistically significant decrease in paroxysmal activity.Conclusions: in patients with uncontrolled seizures, resection of the cerebral lesion associated with the irritative area shows a tendency to obtain better seizure-outcome results than restricted lesionectomy.
Palavra-chave epilepsy tumors
epilepsy surgery
lesionectomy
electrocorticography
Idioma Inglês
Data de publicação 1999-07-01
Publicado em Epilepsia. Philadelphia: Lippincott Williams & Wilkins, v. 40, n. 7, p. 856-864, 1999.
ISSN 0013-9580 (Sherpa/Romeo, fator de impacto)
Publicador Lippincott Williams & Wilkins
Extensão 856-864
Fonte http://dx.doi.org/10.1111/j.1528-1157.1999.tb00791.x
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000081247200006
Endereço permanente http://repositorio.unifesp.br/handle/11600/26098

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta