Placental transfer of ige antibodies against Haemophilus influenzae type b capsular polysaccharide in Brazilian term and preterm newborns

Placental transfer of ige antibodies against Haemophilus influenzae type b capsular polysaccharide in Brazilian term and preterm newborns

Autor Nagao, A. T Autor UNIFESP Google Scholar
Autor UNIFESP Google Scholar
Arslanian, C. Autor UNIFESP Google Scholar
Sole, D. Autor UNIFESP Google Scholar
Naspitz, C. Autor UNIFESP Google Scholar
Carneiro-Sampaio, MMS Autor UNIFESP Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Resumo Placental transfer of antibodies to polysaccharide antigens is still a controversial subject. the incidence of invasive Haemophilus influenzae type b (Hib) infections is high in countries where the vaccine has not been included in routine immunization schedules. in the present work, we proposed to evaluate the natural immune response to nib capsular polysaccharide in term and preterm Brazilian newborns and their respective mothers. Although the means, medians, and ranges of antibody titres in paired maternal and cord sera from preterm neonates were similar, the maternal levels were slightly higher than the cord levels and a poor correlation between these levels was verified. Term neonates showed similar antibody levels to those of their respective mothers and a very significant correlation between these levels was observed.
Idioma Inglês
Data de publicação 1999-06-01
Publicado em Journal of Tropical Pediatrics. Oxford: Oxford Univ Press, v. 45, n. 3, p. 171-173, 1999.
ISSN 0142-6338 (Sherpa/Romeo, fator de impacto)
Publicador Oxford Univ Press
Extensão 171-173
Fonte http://dx.doi.org/10.1093/tropej/45.3.171
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000081136900013
Endereço permanente http://repositorio.unifesp.br/handle/11600/26084

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