Botulinum toxin for oropharyngeal dysphagia: case report of flexible endoscope-guided injection

Botulinum toxin for oropharyngeal dysphagia: case report of flexible endoscope-guided injection

Autor Brant, C. Q. Google Scholar
Siqueira, E. S. Google Scholar
Ferrari, A. P. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Botulinnm toxin (BT) has been used in neurology, ophthalmology, otorhinolaryngology and gastroenterology. Twenty-four patients with oropharyngeal dysphagia treated with BT injection into the cricopharyngeal muscle were reported, with good results in up to 79% of the patients, Different techniques were used to inject BT: percutaneous (guided by electromyography, computed tomography or videofluoroscopy) or direct injection during esophagoscopy (with a rigid esophagoscope), We report the first case of oropharyngeal dysphagia treated by BT injection into the cricopharyngeal muscle using a flexible scope, with clinical, radiological and manometric improvement.A reduction in the disability score 4 to 2 and sustained capacity to maintain adequate oral caloric intake were observed. the patient was also able to have the tracheotomy orifice closed and the gastrostomy tube removed after 3 months, Manometry showed a 38% reduction in the upper esophageal sphincter pressure with the presence of pharyngeal waves that were previously absent. After 1 year of follow-up, the patient was in good condition with mild dysphagia for solid foods. This is another case of complex dysphagia and relative hyperfunction of the cricopharyngeal muscle successfully treated with BT injection.
Idioma Inglês
Data 1999-01-01
Publicado em Diseases of the Esophagus. Carlton: Blackwell Science Asia, v. 12, n. 1, p. 68-73, 1999.
ISSN 1120-8694 (Sherpa/Romeo, fator de impacto)
Editor Blackwell Science Asia
Extensão 68-73
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000083699500015

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