Fetal fibronectin as a predictor of preterm delivery in twin gestations

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dc.contributor.author Oliveira, T.
dc.contributor.author Souza, E. de
dc.contributor.author Mariani-Neto, C.
dc.contributor.author Camano, L.
dc.date.accessioned 2016-01-24T12:30:38Z
dc.date.available 2016-01-24T12:30:38Z
dc.date.issued 1998-08-01
dc.identifier http://dx.doi.org/10.1016/S0020-7292(98)00076-9
dc.identifier.citation International Journal of Gynecology & Obstetrics. Clare: Elsevier Sci Ireland Ltd, v. 62, n. 2, p. 135-139, 1998.
dc.identifier.issn 0020-7292
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/25932
dc.description.abstract Objective: To evaluate fetal fibronectin as a predictor of premature delivery in twin pregnancies. Method: Cervicovaginal secretions were obtained from 52 pregnant women with twin pregnancies between 24 and 34 weeks of gestation. the secretions were analyzed to detect the presence of fetal fibronectin by immediate-reading membrane test. the correlation between the presence of fetal fibronectin and preterm birth was evaluated. in addition, cervical dilatation and effacement were evaluated with each sampling. Result: the sensitivity, specificity, positive predictive value and negative predictive value to predict preterm delivery were 89.3, 50.0, 67.6, and 80.0%, respectively. A positive fetal fibronectin result was associated with a relative risk (RR) for preterm birth of 3.4 (95% CI, 1.2-9.5). A positive fetal fibronectin test associated with cervical dilatation or effacement increased the RR for preterm birth to 4.3 and 7.7, respectively, when compared with those with negative test and without cervical dilatation and effacement. Conclusion: Fetal fibronectin in the cervicovaginal secretions of patients with twin pregnancies is a sensitive predictor of preterm delivery. However, because of its low specificity, the fetal fibronectin test should be evaluated along with cervical changes for better identification of twins likely to develop preterm labor. (C) 1998 International Federation of Gynecology and Obstetrics. en
dc.format.extent 135-139
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof International Journal of Gynecology & Obstetrics
dc.rights Acesso restrito
dc.subject twins en
dc.subject fetal fibronectin en
dc.subject preterm delivery en
dc.title Fetal fibronectin as a predictor of preterm delivery in twin gestations en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Hosp Maternidade Leonor Mendes Barros
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Hosp Maternidade Leonor Mendes Barros, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, São Paulo, Brazil
dc.identifier.doi 10.1016/S0020-7292(98)00076-9
dc.description.source Web of Science
dc.identifier.wos WOS:000075503200003


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