Human leukocyte antigens and malignant essential hypertension

Human leukocyte antigens and malignant essential hypertension

Autor Gerbase-DeLima, M. Google Scholar
Paiva, RLF Google Scholar
Bortolotto, L. A. Google Scholar
Bernardes-Silva, H. Google Scholar
De Lima, JJG Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The purpose of this study was to investigate an association between human leukocyte antigens (HLA) and the susceptibility to malignant hypertension. the presence of HLA-A -B, -DR, and -DQ was determined in 33 white and in 23 mulatto Brazilian patients with malignant essential hypertension. No statistically significant differences were detected between patients and control subjects. It is nevertheless important to note that we have observed an increased frequency of DR3 in the mulatto patients (34.8% v 21.4%). We consider that this finding supports the existence of an HLA-DR3 association with hypertension in the black population, as has been claimed by other authors. (C) 1998 American Journal of Hypertension, Ltd.
Palavra-chave hypertension
genetics
human leukocyte antigen
major histocompatability complex
Idioma Inglês
Data de publicação 1998-06-01
Publicado em American Journal of Hypertension. New York: Elsevier B.V., v. 11, n. 6, p. 729-731, 1998.
ISSN 0895-7061 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 729-731
Fonte http://dx.doi.org/10.1016/S0895-7061(98)00050-8
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000074331600013
Endereço permanente http://repositorio.unifesp.br/handle/11600/25907

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