Inappropriate prescribing of compounded antiobesity formulas in Brazil

Show simple item record Nappo, S. A. De Oliveira, E. M. Morosini, S. 2016-01-24T12:30:34Z 2016-01-24T12:30:34Z 1998-05-01
dc.identifier.citation Pharmacoepidemiology and Drug Safety. W Sussex: John Wiley & Sons Ltd, v. 7, n. 3, p. 207-212, 1998.
dc.identifier.issn 1053-8569
dc.description.abstract Volunteers posing as patients underwent paid medical consultations at the offices of 107 Brazilian doctors (in two Brazilian cities) with the purpose of obtaining an antiobesity prescription. in 80.3% of 71 São Paulo visits, as well as in 47.2% of 36 Recife visits, compounded preparations were prescribed. Four to six active components predominated, but there were prescriptions listing as many as 17 components. All contained anorectic substances and benzodiazepines. Diuretics, thyroid agents, laxatives, medicinal plants, and a variety of other substances were often included. the prescribed doses were frequently above recommended limits, reaching amounts as much as live times the internationally defined standard doses. in some instances two anorectic substances were prescribed simultaneously. Most doctors failed to warn volunteers of the possible occurrence of adverse reactions to the prescribed substances. Furthermore, in the case of all volunteers involved, antiobesity prescriptions would be completely unnecessary, a fact that points to improper medical conduct on the part of doctors. It is concluded that the practice by some Brazilian medical doctors of prescribing manipulation formulas based on anorectic and benzodiazepine drugs is a greater hazard than a benefit to patients. (C) 1998 John Wiley & Sons, Ltd. en
dc.format.extent 207-212
dc.language.iso eng
dc.publisher Wiley-Blackwell
dc.relation.ispartof Pharmacoepidemiology and Drug Safety
dc.rights Acesso restrito
dc.subject medical prescription en
dc.subject antiobesity drugs en
dc.subject anorectic drugs en
dc.subject diethylpropion en
dc.subject fenproporex en
dc.subject magistral formulas en
dc.subject d,1-fenfluramine en
dc.subject d-fenfluramine weight-reducing drugs en
dc.title Inappropriate prescribing of compounded antiobesity formulas in Brazil en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade Federal de Pernambuco (UFPE)
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Dept Psicobiol, BR-04023062 São Paulo, Brazil
dc.description.affiliation Univ Fed Pernambuco, Recife, PE, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Dept Psicobiol, BR-04023062 São Paulo, Brazil
dc.identifier.doi 10.1002/(SICI)1099-1557(199805/06)7:3<207
dc.description.source Web of Science
dc.identifier.wos WOS:000074814800007


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