Legume vicilins (7S storage globulins) inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells

Legume vicilins (7S storage globulins) inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells

Autor Gomes, V. M. Google Scholar
Okorokov, L. A. Google Scholar
Rose, T. L. Google Scholar
Fernandes, KVS Google Scholar
Xavier-Filho, J. Google Scholar
Instituição Univ Estadual Norte Fluminense
Universidade Federal de São Paulo (UNIFESP)
Univ Fed Ceara
Resumo Vicilin (7S storage proteins) isolated from different legume seeds were shown to inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells. the degree of growth inhibition varied with the origin of vicilins. It was more than 90% for vicilins from cowpea (Vigna unguiculata, cultivar pitiuba) and equal to 65% for vicilins from Vigna radiata, in the case of Saccharomyces cerevisae. Vicilins from cowpea seeds inhibited the glucose stimulated acidification of the medium by S. cerevisae up to 60%. We have also observed that vicilins bind to yeast cells. We suggest that vicilins bind to chitin-containing structures of yeast cells and that such association could result in inhibition of H+ pumping, cell growth and spore formation. A final consequence of the yeast growth inhibition by vicilins is (probably) the formation of spores. (C) 1998 Elsevier Science B.V.
Palavra-chave vicilin
7S storage protein
legume seed
chitin-binding protein
H+ pumping
(Saccharomyces cerevisae)
(Candida albicans)
(yeast)
Idioma Inglês
Data de publicação 1998-02-02
Publicado em Biochimica Et Biophysica Acta-general Subjects. Amsterdam: Elsevier B.V., v. 1379, n. 2, p. 207-216, 1998.
ISSN 0304-4165 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 207-216
Fonte http://dx.doi.org/10.1016/S0304-4165(97)00100-1
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000072285000006
Endereço permanente http://repositorio.unifesp.br/handle/11600/25865

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta