American trypanosomiasis

Author Yoshida, N. Google Scholar
Schenkman, S. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Endemic throughout Latin America American trypanosomiasis, or Chagas' disease, caused by Trypanosoma cruzi, represents a great burden for many countries with considerable economic impact in terms of disability-adjusted years of life lost. Although implementation of vector control programmes has proved to be successful in reducing Vectorial transmission, several important questions remain unresolved, There is no chemotherapy available for the millions that are chronically infected, and blood transfusion still poses a risk of transmission, in this study we discuss recent findings that may open new possibilities for a better understanding of the mechanisms of Chagas' disease pathogenesis, for improving diagnostic tests and developing more effective and less toxic drugs for the treatment of T. cruzi infection.
Language English
Date 1997-10-01
Published in Current Opinion in Infectious Diseases. Philadelphia: Lippincott Williams & Wilkins, v. 10, n. 5, p. 351-356, 1997.
ISSN 0951-7375 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 351-356
Origin http://dx.doi.org/10.1097/00001432-199710000-00005
Access rights Closed access
Type Review
Web of Science ID WOS:A1997YC47700005
URI http://repositorio.unifesp.br/handle/11600/25794

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