American trypanosomiasis

Autor Yoshida, N. Google Scholar
Schenkman, S. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Endemic throughout Latin America American trypanosomiasis, or Chagas' disease, caused by Trypanosoma cruzi, represents a great burden for many countries with considerable economic impact in terms of disability-adjusted years of life lost. Although implementation of vector control programmes has proved to be successful in reducing Vectorial transmission, several important questions remain unresolved, There is no chemotherapy available for the millions that are chronically infected, and blood transfusion still poses a risk of transmission, in this study we discuss recent findings that may open new possibilities for a better understanding of the mechanisms of Chagas' disease pathogenesis, for improving diagnostic tests and developing more effective and less toxic drugs for the treatment of T. cruzi infection.
Idioma Inglês
Data 1997-10-01
Publicado em Current Opinion in Infectious Diseases. Philadelphia: Lippincott Williams & Wilkins, v. 10, n. 5, p. 351-356, 1997.
ISSN 0951-7375 (Sherpa/Romeo, fator de impacto)
Editor Lippincott Williams & Wilkins
Extensão 351-356
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:A1997YC47700005

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