Conditioned immunosuppression of lipopolysaccharide-induced antibody response of orally immunized mice

Conditioned immunosuppression of lipopolysaccharide-induced antibody response of orally immunized mice

Autor Morato, E. F. Google Scholar
GerbaseDeLima, M. Google Scholar
Gorczynski, R. M. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
UNIV TORONTO
Resumo BALB/C mice previously conditioned in a paired regimen in which cycophosphamide was given in association with a novel taste in the drinking water (saccharin, SAC) subsequently received LPS (1mg/mouse) by oral gavage. Subgroups of mice were reexposed to SAC or water respectively, and anti-LPS antibody production measured 6 days later using an ELISA/ELISPOT assay. Our data show that the immune response to this T-independent antigen, administered orally, is amenable to conditioned immunosuppression in this model system. (C) 1997 Academic Press.
Idioma Inglês
Data de publicação 1997-06-01
Publicado em Brain Behavior and Immunity. San Diego: Academic Press Inc Jnl-comp Subscriptions, v. 11, n. 2, p. 133-139, 1997.
ISSN 0889-1591 (Sherpa/Romeo, fator de impacto)
Publicador Academic Press Inc Jnl-comp Subscriptions
Extensão 133-139
Fonte http://dx.doi.org/10.1006/brbi.1997.0488
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1997XX33400005
Endereço permanente http://repositorio.unifesp.br/handle/11600/25732

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