Allele frequency of ADH2 and ALDH2 among Brazilians of different ethnic groups

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dc.contributor.author Santos, B. R.
dc.contributor.author Monteiro, M. G.
dc.contributor.author Thomasson, H. R.
dc.date.accessioned 2016-01-24T12:30:20Z
dc.date.available 2016-01-24T12:30:20Z
dc.date.issued 1997-05-01
dc.identifier http://dx.doi.org/10.1016/S0741-8329(96)00066-3
dc.identifier.citation Alcohol. New York: Elsevier B.V., v. 14, n. 3, p. 205-207, 1997.
dc.identifier.issn 0741-8329
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/25720
dc.description.abstract We determined the genotypes of the alcohol dehydrogenase (ALDH) and aldehyde dehydrogenase (ALDH2) loci of different ethnic groups living in Brazil, using saliva DNA amplified by PCR and allele-specific oligonucleotides. Self-reports of flushing reaction after drinking were also studied. the allelic frequencies of ADH2 and ALDH2 were found to be lower than those reported other authors, which might be a result of the admixture origin of the Brazilian population. Variability in facial flushing reaction suggests that other factors play a role in the expression of alcohol-induced flushing. (C) 1997 Elsevier Science Inc. en
dc.format.extent 205-207
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Alcohol
dc.rights Acesso restrito
dc.subject alcohol dehydrogenase en
dc.subject aldehyde dehydrogenase en
dc.subject alcohol en
dc.subject ethanol metabolizing isoenzymes en
dc.subject ethnic differences en
dc.subject genetic polymorphism en
dc.subject alcohol flushing en
dc.title Allele frequency of ADH2 and ALDH2 among Brazilians of different ethnic groups en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade Federal de Uberlândia (UFU)
dc.contributor.institution INDIANA UNIV
dc.description.affiliation ESCOLA PAULISTA MED, DEPT PSYCHOBIOL, BR-04023062 São Paulo, BRAZIL
dc.description.affiliation UNIV FED UBERLANDIA, DEPT PHARMACOL, BR-38400 UBERLANDIA, MG, BRAZIL
dc.description.affiliation INDIANA UNIV, SCH MED, INDIANAPOLIS, in USA
dc.description.affiliationUnifesp ESCOLA PAULISTA MED, DEPT PSYCHOBIOL, BR-04023062 São Paulo, BRAZIL
dc.identifier.doi 10.1016/S0741-8329(96)00066-3
dc.description.source Web of Science
dc.identifier.wos WOS:A1997WZ02500001



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