RESPONSE TO HIGH-DOSE CISPLATIN and ETOPOSIDE in ADVANCED GERM-CELL TUMORS in CHILDREN - RESULTS of the BRAZILIAN GERM-CELL TUMOR STUDY

RESPONSE TO HIGH-DOSE CISPLATIN and ETOPOSIDE in ADVANCED GERM-CELL TUMORS in CHILDREN - RESULTS of the BRAZILIAN GERM-CELL TUMOR STUDY

Autor Lopes, L. F. Google Scholar
Decamargo, B. Google Scholar
Dondonis, M. Google Scholar
Dearaujo, R. A. Google Scholar
Morinaka, E. Google Scholar
Instituição HOSP SANTO ANTONIO
Universidade Federal de Uberlândia (UFU)
HOSP HELIO ANGOTTI
Universidade Federal de São Paulo (UNIFESP)
Resumo A trial was undertaken to assess the efficacy and toxicity of high-dose cisplatin and etoposide in children with newly diagnosed advanced malignant germ cell tumors. A total of eleven children and adolescents were treated with courses of high dose cisplatin 30 mg/m(2)/day and etoposide 120 mg/m(2)/day in five day cycles at 21 day intervals. There were eight girls and three boys, aged between 1 and 16 years (median: 120 months). of nine unresectable tumors, six were in complete remission after three cycles and were completely resected. All patients are alive (median follow-up 17 months). Preliminary results shows that high dose cisplatin and etoposide is effective in controlling advanced malignant germ cell tumor. (C) 1995 Wiley-Liss, Inc.
Palavra-chave GERM CELL TUMORS
HIGH DOSE CISPLATIN and ETOPOSIDE
ADVANCED DISEASE
Idioma Inglês
Data de publicação 1995-11-01
Publicado em Medical and Pediatric Oncology. New York: Wiley-liss, v. 25, n. 5, p. 396-399, 1995.
ISSN 0098-1532 (Sherpa/Romeo, fator de impacto)
Publicador Wiley-Blackwell
Extensão 396-399
Fonte http://dx.doi.org/10.1002/mpo.2950250506
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1995RV93800005
Endereço permanente http://repositorio.unifesp.br/handle/11600/25534

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