The influence of isotonic exercise on cardiac-hypertrophy in arterial-hypertension - impact on cardiac-function and on the capacity for aerobic work

Show simple item record

dc.contributor.author Moreno, H.
dc.contributor.author Cezareti, MLR
dc.contributor.author Piçarro, Ivan da Cruz [UNIFESP]
dc.contributor.author Neto, TLB
dc.contributor.author Martinez, E. E.
dc.contributor.author Saragoca, MAS
dc.date.accessioned 2016-01-24T11:40:27Z
dc.date.available 2016-01-24T11:40:27Z
dc.date.issued 1995-10-01
dc.identifier http://dx.doi.org/10.1016/0300-9629(95)00103-4
dc.identifier.citation Comparative Biochemistry and Physiology A-physiology. Oxford: Pergamon-Elsevier B.V., v. 112, n. 2, p. 313-320, 1995.
dc.identifier.issn 0300-9629
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/25529
dc.description.abstract Intense physical training through isotonic exercises has controversial effects in individuals with moderate to severe hypertension, in this study, normotensive Wistar rats and rats with renovascular hypertension (Goldblatt II) were subjected to intense physical exercise involving two 50-min swimming sessions per day for a period of 12 weeks, At the end of the study, we evaluated the effect of training on arterial pressure, the capacity for aerobic work and cardiac function. Our results demonstrate that intense physical training has no effect on the arterial blood pressure of normotensive rats or of animals with moderate renovascular hypertension, Hypertensive animals with cardiac hypertrophy require a greater period of training in order to attain the same capacity for aerobic work as normotensive rats. This difference may result from an inability of the former animals to increase cardiac compliance, thereby impeding more extensive usage of the Frank-Starling mechanism to subsequently increase the systolic cardiac performance, Cardiac hypertrophy induced by exercise did not summate with that induced by arterial hypertension, Physical exercise normalized the end-diastolic left ventricular pressure in hypertensive animals without any corresponding increase in the compliance of the chamber, the first derivative of left ventricular pulse pressure (+/-dP/dt) was greater in the hypertensive trained group than in the hypertensive sedentary rats, These observations suggest that a systolic dysfunction of the left ventricle involving an elevated residual volume secondary to arterial hypertension may be corrected by physical exercise such as swimming. en
dc.format.extent 313-320
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Comparative Biochemistry and Physiology A-physiology
dc.rights Acesso restrito
dc.subject LEFT VENTRICULAR HYPERTROPHY en
dc.subject PHYSICAL TRAINING en
dc.subject ARTERIAL HYPERTENSION en
dc.subject OXYGEN CONSUMPTION en
dc.subject CARDIAC COMPLIANCE en
dc.title The influence of isotonic exercise on cardiac-hypertrophy in arterial-hypertension - impact on cardiac-function and on the capacity for aerobic work en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation ESCOLA PAULISTA MED,DEPT CARDIOL,São Paulo,BRAZIL
dc.description.affiliation ESCOLA PAULISTA MED,DEPT NEPHROL,São Paulo,BRAZIL
dc.description.affiliation ESCOLA PAULISTA MED,DEPT EXERCISE PHYSIOL,São Paulo,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DEPT CARDIOL,São Paulo,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DEPT NEPHROL,São Paulo,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DEPT EXERCISE PHYSIOL,São Paulo,BRAZIL
dc.identifier.doi 10.1016/0300-9629(95)00103-4
dc.description.source Web of Science
dc.identifier.wos WOS:A1995TB71900007



File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search


Browse

Statistics

My Account