ASSESSING the EFFICACY of A MIXED VACCINATION STRATEGY AGAINST RUBELLA in SAO-PAULO, BRAZIL

ASSESSING the EFFICACY of A MIXED VACCINATION STRATEGY AGAINST RUBELLA in SAO-PAULO, BRAZIL

Autor Massad, E. Google Scholar
Azevedoneto, R. S. Google Scholar
Burattini, M. N. Google Scholar
Zanetta, DMT Google Scholar
Coutinho, FAB Google Scholar
Yang, H. M. Google Scholar
Moraes, J. C. Google Scholar
Pannuti, C. S. Google Scholar
Souza, VAUF Google Scholar
Silveira, ASB Google Scholar
Struchiner, C. J. Google Scholar
Oselka, G. W. Google Scholar
Camargo, MCC Google Scholar
Omoto, T. M. Google Scholar
Passos, S. D. Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
FAC CIENCIAS MED SANTA CASA
SECRETARIA ESTADO SAUDE São Paulo
FIOCRUZ MS
Resumo Background. in 1992 a major vaccination strategy against measles-mumps-rubella was introduced in the State of São Paulo, Brazil. This strategy was based on mathematical models and comprised a pulse vaccination covering all children aged 1-10 years, followed by the inclusion of this vaccine in the routine calendar at 15 months of age. the present work reports the evaluation of the efficacy of this mixed vaccination strategy.Methods. A rubella seroprevalence survey was carried out immediately and one year after the campaign, comprising 4953 children aged 1-15 years.Results. We show that average rubella seroprevalence increased from 0.40 to 0.97 and that the reported number of congenital rubella syndrome (CRS) cases dropped dramatically,Conclusions. the mixed vaccination strategy adopted against rubella has proved to be very effective in reducing the number of CRS cases in São Paulo.
Palavra-chave RUBELLA
CRS
VACCINATION
SEROEPIDEMIOLOGY
CONTROL STRATEGIES
Idioma Inglês
Data de publicação 1995-08-01
Publicado em International Journal of Epidemiology. Oxford: Oxford Univ Press United Kingdom, v. 24, n. 4, p. 842-850, 1995.
ISSN 0300-5771 (Sherpa/Romeo, fator de impacto)
Publicador Oxford Univ Press United Kingdom
Extensão 842-850
Fonte http://dx.doi.org/10.1093/ije/24.4.842
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1995RQ19200025
Endereço permanente http://repositorio.unifesp.br/handle/11600/25521

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