GLYCOSAMINOGLYCAN DISTRIBUTION in ATHEROSCLEROTIC SAPHENOUS-VEIN GRAFTS

GLYCOSAMINOGLYCAN DISTRIBUTION in ATHEROSCLEROTIC SAPHENOUS-VEIN GRAFTS

Autor Marquezini, M. V. Google Scholar
Strunz, CMC Google Scholar
Dallan, LAO Google Scholar
Toledo, OMS Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo Glycosaminoglycan composition of normal saphenous veins and atherosclerotic saphenous vein grafts is reported. Dermatan sulfate is the main glycosaminoglycan present in both normal saphenous veins and saphenous vein grafts. These tissues also contain chondroitin sulfate and heparan sulfate. Although the total amount of glycosaminoglycans decreased in the grafts (compared with normal saphenous veins), the grafts showed an increase in the relative amounts of dermatan sulfate and chondroitin sulfate. Heparan sulfate was decreased, compared with normal controls. These findings suggest the involvement of blood vessel glycosaminoglycans (not only the arterial glycosaminoglycans) in the process of atherosclerosis.
Palavra-chave ATHEROSCLEROSIS
GLYCOSAMINOGLYCANS
SAPHENOUS VEIN GRAFT
REVASCULARIZATION
Idioma Inglês
Data de publicação 1995-03-01
Publicado em Cardiology. Basel: Karger, v. 86, n. 2, p. 143-146, 1995.
ISSN 0008-6312 (Sherpa/Romeo, fator de impacto)
Publicador Karger
Extensão 143-146
Fonte http://dx.doi.org/10.1159/000176860
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1995QH71200009
Endereço permanente http://repositorio.unifesp.br/handle/11600/25477

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