CYTOGENETIC ASPECTS of WERNERS-SYNDROME LYMPHOCYTE-CULTURES

CYTOGENETIC ASPECTS of WERNERS-SYNDROME LYMPHOCYTE-CULTURES

Autor Melaragno, M. I. Google Scholar
Pagni, D. Google Scholar
Smith, MDC Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Lymphocyte cultures from five patients with Werner's syndrome (WS) and five healthy controls revealed significantly slower proliferation kinetics in four out of five patients. Higher frequencies of chromosome aberration and aneuploidy were also present with evidence of variegated translocation mosaicism in one of the patients. the study revealed no differences in sister chromatid exchange frequencies.
Assunto WERNERS SYNDROME
PREMATURE AGING
LYMPHOCYTE PROLIFERATION
CHROMOSOME ABERRATION
SISTER CHROMATID EXCHANGE
Idioma Inglês
Data 1995-03-01
Publicado em Mechanisms of Ageing and Development. Clare: Elsevier Sci Publ Ireland Ltd, v. 78, n. 2, p. 117-122, 1995.
ISSN 0047-6374 (Sherpa/Romeo, fator de impacto)
Editor Elsevier B.V.
Extensão 117-122
Fonte http://dx.doi.org/10.1016/0047-6374(94)01530-Y
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1995QP16400004
URI http://repositorio.unifesp.br/handle/11600/25469

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