CYTOGENETIC ASPECTS of WERNERS-SYNDROME LYMPHOCYTE-CULTURES

CYTOGENETIC ASPECTS of WERNERS-SYNDROME LYMPHOCYTE-CULTURES

Autor Melaragno, M. I. Google Scholar
Pagni, D. Google Scholar
Smith, MDC Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Lymphocyte cultures from five patients with Werner's syndrome (WS) and five healthy controls revealed significantly slower proliferation kinetics in four out of five patients. Higher frequencies of chromosome aberration and aneuploidy were also present with evidence of variegated translocation mosaicism in one of the patients. the study revealed no differences in sister chromatid exchange frequencies.
Palavra-chave WERNERS SYNDROME
PREMATURE AGING
LYMPHOCYTE PROLIFERATION
CHROMOSOME ABERRATION
SISTER CHROMATID EXCHANGE
Idioma Inglês
Data de publicação 1995-03-01
Publicado em Mechanisms of Ageing and Development. Clare: Elsevier Sci Publ Ireland Ltd, v. 78, n. 2, p. 117-122, 1995.
ISSN 0047-6374 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 117-122
Fonte http://dx.doi.org/10.1016/0047-6374(94)01530-Y
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1995QP16400004
Endereço permanente http://repositorio.unifesp.br/handle/11600/25469

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta