CHOLESTEROL in the DISTAL PORTIONS of DIFFERENTIATING and FULLY DIFFERENTIATED RAT ODONTOBLASTS OBSERVED BY FREEZE-FRACTURE

CHOLESTEROL in the DISTAL PORTIONS of DIFFERENTIATING and FULLY DIFFERENTIATED RAT ODONTOBLASTS OBSERVED BY FREEZE-FRACTURE

Autor Franklin, D. L. Google Scholar
Aranachavez, V. E. Google Scholar
Katchburian, E. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
UNIV LEEDS
Universidade de São Paulo (USP)
LONDON HOSP
Resumo Freeze-fracture replicas of rat molar tooth germs in conjunction with the 3-beta-hydroxysterol marker filipin were used to study the distribution of cholesterol in the distal portions of odontoblast plasma membrane. Filipin-sterol deformations (interactions) appeared as clusters interspersed with deformation-free regions on the distal plasma membrane of early differentiating odontoblasts. in fully differentiated odontoblasts, the whole distal membrane, including the process, was occupied by packed deformations with no free regions. It seems that early developing odontoblasts are poorer in cholesterol than the fully differentiated cells. As the content and/or distribution of 3-beta-hydroxysterols (cholesterol) is known to influence membrane fluidity, the low cholesterol content of early differentiating odontoblasts might be related to the fluidity required for the budding off of matrix vesicles.
Palavra-chave FREEZE-FRACTURE
ODONTOBLASTS
FILIPIN
MATRIX VESICLES
Idioma Inglês
Data de publicação 1994-09-01
Publicado em Archives of Oral Biology. Oxford: Pergamon-Elsevier B.V., v. 39, n. 9, p. 817-819, 1994.
ISSN 0003-9969 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 817-819
Fonte http://dx.doi.org/10.1016/0003-9969(94)90011-6
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1994PK50000011
Endereço permanente http://repositorio.unifesp.br/handle/11600/25430

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