REPETITIVE SEQUENCES in the RIBOSOMAL INTERGENIC SPACER of TRYPANOSOMA-CRUZI

REPETITIVE SEQUENCES in the RIBOSOMAL INTERGENIC SPACER of TRYPANOSOMA-CRUZI

Autor Novak, E. M. Google Scholar
Demello, M. P. Google Scholar
Gomes, HBM Google Scholar
GALINDO, I Google Scholar
Guevara, P. Google Scholar
Ramirez, J. L. Google Scholar
Dasilveria, J. F. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
CENT UNIV VENEZUELA
Resumo A fragment of Trypanosoma cruzi ribosomal intergenic spacer (IGS) located at 6.7 kb from the 3' end of the 24S rRNA gene was analyzed. This IGS fragment is characterized by the presence of three types of repetitive elements (designated Spacer Repetitive Elements, SRE), short direct repeats (5-6 bp) and chi-like recombinational sequences. SRE elements are composed of relatively short repeats (43-145 bp) which show variabilities consisting of nucleotide changes, insertions and deletions. SRE-1 element (145 bp) has a short oligo(dA) tail at the end of the repeat and can be found flanked by other SRE elements. SRE elements are species-specific, suggesting that probes based on them may be diagnostic for Trypanosoma cruzi.
Palavra-chave TRYPANOSOMA-CRUZI
RIBOSOMAL INTERGENIC SPACER
SPACER REPETITIVE ELEMENTS
SPECIES-SPECIFIC SEQUENCE
CHI-LIKE SEQUENCE
Idioma Inglês
Data de publicação 1993-08-01
Publicado em Molecular and Biochemical Parasitology. Amsterdam: Elsevier B.V., v. 60, n. 2, p. 273-280, 1993.
ISSN 0166-6851 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 273-280
Fonte http://dx.doi.org/10.1016/0166-6851(93)90138-N
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1993LR65100011
Endereço permanente http://repositorio.unifesp.br/handle/11600/25344

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