HISTOMORPHOMETRY of IMMATURE RAT TESTIS AFTER HEATING

HISTOMORPHOMETRY of IMMATURE RAT TESTIS AFTER HEATING

Autor Miraglia, S. M. Google Scholar
Hayashi, H. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The scrotal testes of albino rats aged 35 and 45 days were immersed in water at constant temperatures of 43-degrees-C, 44-degrees-C, or 45-degrees-C for periods of 15-45 min in a special heating device. At an age of 60 days, the rats were mated in individual cages with two primiparous rats each. At an age of 90 days, they were killed and their testes were histologically processed. Rats with testes that had been subjected to heating when the animals were 45 days old showed both alterations of the seminiferous tubules and a decrease in fertilizing capacity. the effect of heat was greater in animals at 45 than at 35 days of age. in heat-treated testes, tubules contained PAS-positive concretion, sometimes engulfed by macrophage-derived giant cells and multinucleate cells derived from spermatids that failed to separate during spermiogenesis. the decrease in testicular volume observed after heat treatment was due mainly to reduced parenchymal volume. Thermic lability of seminiferous stem cells increases with age until adulthood, and recovery from heat injury declines. (C)1993 Wiley-Liss, Inc.
Idioma Inglês
Data de publicação 1993-07-01
Publicado em Journal of Morphology. New York: Wiley-liss, v. 217, n. 1, p. 65-74, 1993.
ISSN 0362-2525 (Sherpa/Romeo, fator de impacto)
Publicador Wiley-Blackwell
Extensão 65-74
Fonte http://dx.doi.org/10.1002/jmor.1052170106
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1993LL80400005
Endereço permanente http://repositorio.unifesp.br/handle/11600/25336

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