MODELING the INTERACTION BETWEEN AIDS and TUBERCULOSIS

MODELING the INTERACTION BETWEEN AIDS and TUBERCULOSIS

Autor Massad, E. Google Scholar
Burattini, Marcelo Nascimento Autor UNIFESP Google Scholar
Coutinho, FAB Google Scholar
Yang, H. M. Google Scholar
Raimundo, S. M. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo A deterministic model is proposed for the study of the dynamics of acquired immunodeficiency syndrome (AIDS) and tuberculosis (TB) co-infection. the model is comprised by a set of sixteen ordinary differential equations representing different states of both diseases, and it is intended to provide a theoretical framework for the study of the interaction between both infections. Numerical simulations of the model resulted in three striking outcomes: first, the pathogenicity of Human Immunodeficiency Virus (HIV) is enhanced by the presence of TB, and vice-versa; second, the prevalence of AIDS is higher in the presence of TB; and third, relative risk analysis demonstrated a much stronger influence of AIDS on TB than the other way around.
Idioma Inglês
Data de publicação 1993-05-01
Publicado em Mathematical and Computer Modelling. Oxford: Pergamon-Elsevier B.V., v. 17, n. 9, p. 7-21, 1993.
ISSN 0895-7177 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 7-21
Fonte http://dx.doi.org/10.1016/0895-7177(93)90013-O
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:A1993LL84800002
Endereço permanente http://repositorio.unifesp.br/handle/11600/25320

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