Serum laminin in hepatic schistosomiasis

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dc.contributor.author Parise, Edison Roberto [UNIFESP]
dc.contributor.author Rosa, Heitor
dc.date.accessioned 2016-01-24T11:40:06Z
dc.date.available 2016-01-24T11:40:06Z
dc.date.issued 1992-03-01
dc.identifier http://dx.doi.org/10.1016/0035-9203(92)90560-Y
dc.identifier.citation Transactions of the Royal Society of Tropical Medicine and Hygiene. London: Royal Soc Tropical Medicine, v. 86, n. 2, p. 179-181, 1992.
dc.identifier.issn 0035-9203
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/25243
dc.description.abstract Serum laminin levels were measured in patients with chronic hepatic schistosomiasis. A significant increase in the mean serum laminin level was observed in 14 patients with hepatosplenic schistosomiasis (2-57 +/- 0.83 units/ml [standard deviation]) compared to the level in 10 patients with the hepatointestinal form of the disease (1.38 +/- 0.45 units/ml) and in the control group of 10 (1.15 +/- 0.31 units/ml). in the hepatosplenic patients there was a significant direct relation between serum laminin and percutaneous splenic pulp pressure (r = 0.68). However, this relation was not observed with either liver function tests or levels of N-terminal propeptides of type III procollagen. These findings are compatible with an increased production of laminin in hepatosplenic schistosomiasis, which may be related to the observed enlarged liver and spleen basement membranes in such disease. en
dc.format.extent 179-181
dc.language.iso eng
dc.publisher Royal Soc Tropical Medicine
dc.relation.ispartof Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.rights Acesso restrito
dc.title Serum laminin in hepatic schistosomiasis en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution UNIV FED GIOAS
dc.description.affiliation ESCOLA PAULISTA MED SCH,CLIN GASTROENTEROL UNIT,BR-04023 São Paulo,BRAZIL
dc.description.affiliation UNIV FED GIOAS,CLIN GASTROENTEROL UNIT,GOIANIA,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED SCH,CLIN GASTROENTEROL UNIT,BR-04023 São Paulo,BRAZIL
dc.identifier.doi 10.1016/0035-9203(92)90560-Y
dc.description.source Web of Science
dc.identifier.wos WOS:A1992HV02200022



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