Delayed-hypersensitivity skin-tests in prognosis of human-immunodeficiency-virus infection

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dc.contributor.author Zeballos, R. S.
dc.contributor.author Cavalcante, N.
dc.contributor.author Freire, Carlos Alberto Reis [UNIFESP]
dc.contributor.author Hernandez, H. J.
dc.contributor.author Longo, I. M.
dc.contributor.author Peixinho, Z. F.
dc.contributor.author Moura, N. C.
dc.contributor.author Mendes, N. F.
dc.date.accessioned 2016-01-24T11:40:05Z
dc.date.available 2016-01-24T11:40:05Z
dc.date.issued 1992-01-01
dc.identifier http://dx.doi.org/10.1002/jcla.1860060303
dc.identifier.citation Journal of Clinical Laboratory Analysis. New York: Wiley-liss, v. 6, n. 3, p. 119-122, 1992.
dc.identifier.issn 0887-8013
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/25234
dc.description.abstract Delayed hypersensitivity skin tests (DHST) with recall antigens were investigated as prognostic markers in five different approaches. in the first study, 42 acquired immunodeficiency syndrome (AIDS) patients (IVb, IVcl, IVd, and IVe; MMWR 35:334-339,1986) 26 AIDS-related complex (ARC) patients (IVa and IVc2), and 98 asymptomatic patients (II and III) were evaluated with candidin, tricophytin, PPD and streptokinase-streptodornase. in the second study, 10 patients (II and III) were evaluated sequentially with the same antigens. in the third, 45 patients with at least two positive skin tests (reactors) were followed for one year and evaluated every 6 months with the same antigens. in the fourth, 16 reactors were followed and evaluated every 3 months with the same antigens. We measured the interval from the time at which patients first presented with only one or no positive DHST until the development of ARC or AIDS. in the last study, the correlation between absolute number of CD4+ lymphocytes and the number of DHST was studied in 151 patients. We found that the decrease in reactiveness to DHST correlated directly with the progression to AIDS, demonstrating the usefulness of this simple procedure as a valid prognostic marker. en
dc.format.extent 119-122
dc.language.iso eng
dc.publisher Wiley-Blackwell
dc.relation.ispartof Journal of Clinical Laboratory Analysis
dc.rights Acesso restrito
dc.subject DHST en
dc.subject HIV en
dc.subject AIDS en
dc.title Delayed-hypersensitivity skin-tests in prognosis of human-immunodeficiency-virus infection en
dc.type Artigo
dc.rights.license http://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation ESCOLA PAULISTA MED SCH,BR-04023 São Paulo,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED SCH,BR-04023 São Paulo,BRAZIL
dc.identifier.doi 10.1002/jcla.1860060303
dc.description.source Web of Science
dc.identifier.wos WOS:A1992HR20300002



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