RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP

Autor	Levin, M. J. Dasilveira, J. F. Frasch, ACC Camargo, M. E. Lafon, S. Degrave, W. M. Rangelaldao, R.
Instituição	LAB FLEURY Universidade Federal de São Paulo (UNIFESP) FDN CAMPOMAR FDN OSWALDO CRUZ UNIV SIMON BOLIVAR
Resumo	A workshop organized by the Ibero-American Project of Biotechnology evaluated the diagnostic potential of several cloned Trypanosoma cruzi recombinant antigens for Chagas' disease serodiagnosis. A set of recombinants, Antigen 2, Antigen 13, SAPA, H49, A13, JL5, JL7, JL8, JL9, and RA1 provided by three different South American laboratories were probed with a panel of 236 South American serum samples. Antigens JL7, H49, Antigen 2, and A13 scored as the best diagnostic recombinant reagents. the results suggested that the main advantage of using cloned peptides for chronic Chagas' disease diagnosis resided in their highly specific immunoreactive properties.
Assunto	TRYPANOSOMA-CRUZI DIAGNOSIS CHAGAS DISEASE TRYPANOSOMA-CRUZI RECOMBINANT ANTIGENS IMMUNOASSAY
Idioma	Inglês
Data	1991-12-01
Publicado em	Fems Microbiology Immunology. Amsterdam: Elsevier B.V., v. 89, n. 1, p. 11-19, 1991.
ISSN	0920-8534 (Sherpa/Romeo, fator de impacto)
Editor	Elsevier B.V.
Extensão	11-19
Fonte	http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.x
Direito de acesso	Acesso aberto
Tipo	Resenha
Web of Science	WOS:A1991GZ12200002
URI	http://repositorio.unifesp.br/handle/11600/25230

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