RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP

RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP

Autor Levin, M. J. Google Scholar
Dasilveira, J. F. Google Scholar
Frasch, ACC Google Scholar
Camargo, M. E. Google Scholar
Lafon, S. Google Scholar
Degrave, W. M. Google Scholar
Rangelaldao, R. Google Scholar
Instituição LAB FLEURY
Universidade Federal de São Paulo (UNIFESP)
FDN CAMPOMAR
FDN OSWALDO CRUZ
UNIV SIMON BOLIVAR
Resumo A workshop organized by the Ibero-American Project of Biotechnology evaluated the diagnostic potential of several cloned Trypanosoma cruzi recombinant antigens for Chagas' disease serodiagnosis. A set of recombinants, Antigen 2, Antigen 13, SAPA, H49, A13, JL5, JL7, JL8, JL9, and RA1 provided by three different South American laboratories were probed with a panel of 236 South American serum samples. Antigens JL7, H49, Antigen 2, and A13 scored as the best diagnostic recombinant reagents. the results suggested that the main advantage of using cloned peptides for chronic Chagas' disease diagnosis resided in their highly specific immunoreactive properties.
Palavra-chave TRYPANOSOMA-CRUZI
DIAGNOSIS
CHAGAS DISEASE
TRYPANOSOMA-CRUZI RECOMBINANT ANTIGENS
IMMUNOASSAY
Idioma Inglês
Data de publicação 1991-12-01
Publicado em Fems Microbiology Immunology. Amsterdam: Elsevier B.V., v. 89, n. 1, p. 11-19, 1991.
ISSN 0920-8534 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 11-19
Fonte http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.x
Direito de acesso Acesso aberto Open Access
Tipo Resenha
Web of Science WOS:A1991GZ12200002
Endereço permanente http://repositorio.unifesp.br/handle/11600/25230

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