PRENATAL STRESS and EMOTIONAL RESPONSE of ADULT OFFSPRING

PRENATAL STRESS and EMOTIONAL RESPONSE of ADULT OFFSPRING

Autor Suchecki, D. Google Scholar
Neto, J. P. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Resumo Pregnant dams were subjected to REM sleep deprivation during different stages of pregnancy. Pups were reared by their biological mothers and tested as adults for susceptibility to PTZ-induced convulsions, and ambulation and defecation in an open-field arena. Adrenal weights were taken at this time. Those animals whose mothers had been stressed during the first trimester showed a reduction in ambulatory behavior measured in the open field, and a reduction in adrenal weight after open-field exposure. Subjects exposed to prenatal stress (PNS) during the 2nd trimester showed an increased susceptibility to PTZ-induced clonic convulsions, and a reduction in adrenal weight after PTZ administration and open-field exposure. Finally, subjects exposed to PNS during the third trimester showed a reduction in susceptibility to PTZ compared with 2nd week PNS pups. the results showed different patterns of prenatal stress-induced behavioral and physiological changes, depending on the developmental stage in which the stress was applied.
Palavra-chave PRENATAL STRESS
EMOTIONAL RESPONSE
CONVULSIONS
OPEN FIELD
ADRENALS
Idioma Inglês
Data de publicação 1991-03-01
Publicado em Physiology & Behavior. Oxford: Pergamon-Elsevier B.V., v. 49, n. 3, p. 423-426, 1991.
ISSN 0031-9384 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 423-426
Fonte http://dx.doi.org/10.1016/0031-9384(91)90259-Q
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:A1991FE04700003
Endereço permanente http://repositorio.unifesp.br/handle/11600/25193

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