Relação entre economia de corrida e perfil imunológico em maratonistas

Relação entre economia de corrida e perfil imunológico em maratonistas

Alternative title Relationship between running economy in immune profile of marathon runners
Author Luna Junior, Luiz Antonio Autor UNIFESP Google Scholar
Advisor Vaisberg, Mauro Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Graduate program Medicina (Otorrinolaringologia) – EPM
Abstract A economia de corrida e definida como oa taxa de consumo de oxigenio necessaria para correr a uma dada velocidadeo e expressa a relacao entre gasto energetico e o trabalho realizado. Todavia, ajustes no volume e intensidade dos treinos para melhorar a performance do atleta pode resultar em diferentes graus de microtraumas desencadeando uma resposta inflamatoria. O objetivo deste trabalho foi investigar a correlacao entre o perfil imunologico, induzido pelo exercicio extenuante, com a economia de corrida avaliada em maratonistas em repouso e apos a maratona. Vinte e dois maratonistas que participaram da maratona internacional de São Paulo de 2012 realizaram teste cardiopulmonar incremental, teste de economia de corrida e coleta de sangue pre, imediatamente apos e 72hs apos a maratona para analise do perfil de citocinas. A IL-6 teve uma significativa correlacao positiva com a economia de corrida dos maratonistas (p<0,05). Nao houve correlacao entre as citocinas IL-1&#946;, IL-4, IL-8, IL-10 e TNF-&#945; pre, imediatamente apos e 72hs apos a maratona e a EC dos maratonistas, assim como, o tempo de chegada da maratona nao teve correlacao com a EC dos maratonistas. Desta forma nossos resultados sugerem que corredores mais economicos sao menos inflamados que corredores menos economicos

Running economy is defined as "the rate of oxygen consumption required to run at a given speed" and expresses the relationship between energy expenditure and work. However, adjustments to the volume and intensity of training to improve athletic performance may result in different degrees of microtraumas triggering an inflammatory response. The aim of this study was to investigate the correlation between the immunological profile induced by strenuous exercise with running economy assessed marathoners at rest and after a marathon. Twenty-two marathon runners who participated in the São Paulo International 2012 held incremental cardiopulmonary exercise test, running economy and blood sampling before, immediately after and 72h after the marathon for analysis of cytokine profile. IL-6 had a significant positive correlation with the running economy of marathoners (p <0,05). There was no correlation between IL-1β, IL-4, IL-8, IL-10 and TNF-α before, immediately after and 72h after a marathon of marathon runners and EC, as well as the arrival time of the marathon was not correlation with the EC marathoners. Patients with heart failure have muscle atrophy and decline of VO2max and VO2 peak, associated with increased IL-6, while studies in healthy subjects and without inflammatory activity relate better performance with baseline IL-6 lower. Thus our results suggest that economic corridors are less inflamed that less economical runners.
Keywords Humanos
Corrida/fisiologia
Consumo de Oxigênio/imunologia
Citocinas/imunologia
Desempenho Atlético
Exercício
Race/physiology
Oxygen Consumption/immunology
Cytokines/immunology
Athletic performance
Exercise
Humanos
Language Portuguese
Date 2013
Published in LUNA JUNIOR, Luiz Antonio. Relação entre economia de corrida e perfil imunológico em maratonistas. 2013. 49 f. Dissertação (Mestrado em Ciências) - Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2013.
Publisher Universidade Federal de São Paulo (UNIFESP)
Extent 48 p.
Access rights Open access Open Access
Type Dissertation
URI http://repositorio.unifesp.br/handle/11600/23164

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