Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest

Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest

Autor Suffredini, I.b. Google Scholar
Sader, Helio Silva Autor UNIFESP Google Scholar
Gonçalves, Azizedite Guedes Google Scholar
Reis, Adriana O. Autor UNIFESP Google Scholar
Gales, Ana Cristina Autor UNIFESP Google Scholar
Varella, Antonio Drauzio Google Scholar
Younes, Riad Naim Google Scholar
Instituição Universidade Paulista Laboratório de Extração
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do Maranhão Centro de Ciências Biológicas e da Saúde
Resumo More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.
Palavra-chave Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
Idioma Inglês
Data de publicação 2004-03-01
Publicado em Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 37, n. 3, p. 379-384, 2004.
ISSN 0100-879X (Sherpa/Romeo, fator de impacto)
Publicador Associação Brasileira de Divulgação Científica
Extensão 379-384
Fonte http://dx.doi.org/10.1590/S0100-879X2004000300015
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000220371600015
SciELO S0100-879X2004000300015 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/2031

Exibir registro completo




Arquivo

Nome: S0100-879X2004000300015.pdf
Tamanho: 505.8KB
Formato: PDF
Descrição:
Abrir arquivo

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta