Detection of cytotoxic necrotizing factor types 1 and 2 among fecal Escherichia coli isolates from brazilian children with and without diarrhea

Detection of cytotoxic necrotizing factor types 1 and 2 among fecal Escherichia coli isolates from brazilian children with and without diarrhea

Autor Tavechio, Ana Terezinha Google Scholar
Marques, Lilian Regina M Google Scholar
Abe, Cecilia Mari Autor UNIFESP Google Scholar
Gomes, Tania Aparecida Tardelli Autor UNIFESP Google Scholar
Instituição Instituto Adolfo Lutz Seção de Bacteriologia
Universidade Federal de São Paulo (UNIFESP)
Resumo The enteropathogenic role of cytotoxic necrotizing factor (CNF)-producing Escherichia coli was investigated by searching cnf genes among 2074 isolates from 200 children with and 200 without acute diarrhea in Brazil. Fourteen (7%) cases versus 10 (5%) control children carried at least one cnf positive isolate (P = 0.50) and most isolates expressed CNF type 1. DNA sequences of virulence factors of extraintestinal pathogenic E. coli (ExPEC) were detected in 78.6% of CNF1-producing isolates. Besides not being associated with human acute diarrhea, the CNF1-producing isolates here identified may represent potential ExPEC transitorily composing the normal intestinal flora.
Palavra-chave Escherichia coli
cytotoxins
cytotoxic necrotizing factor
adhesins
Idioma Inglês
Data de publicação 2004-02-01
Publicado em Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 99, n. 1, p. 81-83, 2004.
ISSN 0074-0276 (Sherpa/Romeo)
Publicador Instituto Oswaldo Cruz, Ministério da Saúde
Extensão 81-83
Fonte http://dx.doi.org/10.1590/S0074-02762004000100014
Direito de acesso Acesso aberto Open Access
Tipo Artigo
SciELO S0074-02762004000100014 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/2014

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